Jens Schmidt Selected Research

Inclusion Body Myositis

11/2021	Inflammatory myopathies: shedding light on promising agents and combination therapies in clinical trials.
1/2018	Current Classification and Management of Inflammatory Myopathies.
1/2018	The EuroMyositis registry: an international collaborative tool to facilitate myositis research.
4/2016	Molecular treatment effects of alemtuzumab in skeletal muscles of patients with IBM.
9/2015	HMGB1 and RAGE in skeletal muscle inflammation: Implications for protein accumulation in inclusion body myositis.
5/2013	Update on treatment of inclusion body myositis.
3/2013	Cell stress molecules in the skeletal muscle of GNE myopathy.
12/2012	Provision of an explanation for the inefficacy of immunotherapy in sporadic inclusion body myositis: quantitative assessment of inflammation and β-amyloid in the muscle.
4/2012	Nitric oxide stress in sporadic inclusion body myositis muscle fibres: inhibition of inducible nitric oxide synthase prevents interleukin-1β-induced accumulation of β-amyloid and cell death.
2/2011	TNF-alpha induces macroautophagy and regulates MHC class II expression in human skeletal muscle cells.

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Jens Schmidt Research Topics

Disease

17	Inflammation (Inflammations) 01/2022 - 05/2004
15	Inclusion Body Myositis 11/2021 - 05/2004
13	Myositis (Idiopathic Inflammatory Myopathies) 01/2022 - 05/2008
5	Muscular Diseases (Myopathy) 02/2022 - 02/2011
5	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 06/2008 - 08/2003
4	Neoplasms (Cancer) 01/2021 - 05/2013
4	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2020 - 05/2004
4	Dermatomyositis (Dermatopolymyositis) 11/2019 - 05/2004
4	Multiple Sclerosis 06/2008 - 08/2003
3	Polymyositis 01/2018 - 05/2004
3	Disease Progression 05/2013 - 07/2007
2	Autoimmune Diseases (Autoimmune Disease) 02/2022 - 08/2005
2	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2021 - 01/2018
2	Deglutition Disorders (Dysphagia) 01/2020 - 01/2018
2	Pain (Aches) 01/2019 - 01/2018
2	Dementia (Dementias) 01/2016 - 04/2012
2	Muscular Dystrophies (Muscular Dystrophy) 09/2015 - 04/2012
1	Muscle Weakness 01/2022
1	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 10/2020
1	Antisynthetase syndrome 02/2020
1	Body Weight (Weight, Body) 01/2020
1	Wasting Syndrome (Wasting Disease) 01/2020
1	Myalgia 01/2020
1	Myotonia 01/2019
1	Muscle Cramp (Cramp) 01/2019
1	Chronic Disease (Chronic Diseases) 01/2018
1	Diabetic Neuropathies (Diabetic Neuropathy) 01/2018
1	Metachromatic Leukodystrophy (Sulfatide Lipidosis) 01/2016
1	Autoimmune Diseases of the Nervous System 06/2015
1	Rhabdomyosarcoma 02/2013
1	Muscular Atrophy (Muscle Atrophy) 05/2012

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 01/2017 - 05/2007
7	Amyloid (Amyloid Fibrils)IBA 03/2013 - 05/2007
5	Messenger RNA (mRNA)IBA 09/2015 - 05/2004
5	Prednisolone (Predate)FDA LinkGeneric 06/2015 - 08/2003
4	AntibodiesIBA 01/2022 - 05/2013
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2011 - 08/2003
3	AutoantibodiesIBA 01/2022 - 01/2016
3	Immunoglobulin G (IgG)IBA 01/2020 - 05/2013
3	Amyloid beta-PeptidesIBA 05/2008 - 05/2007
2	Oxidoreductases (Dehydrogenase)IBA 02/2022 - 05/2004
2	Ligases (Synthetase)IBA 02/2022 - 01/2018
2	Rituximab (Mabthera)FDA Link 01/2022 - 11/2021
2	Creatine Kinase (Creatine Phosphokinase)IBA 01/2021 - 01/2018
2	CytokinesIBA 01/2018 - 01/2007
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 03/2013 - 04/2012
2	ChemokinesIBA 05/2008 - 01/2007
2	Monoclonal AntibodiesIBA 08/2005 - 07/2003
2	Liposomes (Liposome)IBA 09/2003 - 08/2003
2	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 09/2003 - 08/2003
1	Hydroxymethylglutaryl CoA Reductases (HMG CoA Reductase)IBA 02/2022
1	glutaryl-coenzyme A (glutaryl-CoA)IBA 02/2022
1	Abatacept (Orencia)FDA Link 11/2021
1	sifalimumabIBA 11/2021
1	Biological ProductsIBA 11/2021
1	Sirolimus (Rapamycin)FDA Link 11/2021
1	Janus Kinase InhibitorsIBA 11/2021
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2021
1	Botulinum Toxins (Botulinum Toxin)IBA 01/2020
1	DystrophinIBA 01/2020
1	SolutionsIBA 01/2020
1	Glycoproteins (Glycoprotein)IBA 01/2020
1	transcriptional intermediary factor 1IBA 11/2019
1	Gabapentin (Neurontin)FDA LinkGeneric 01/2019
1	Amitriptyline (Elavil)FDA LinkGeneric 01/2019
1	Carbamazepine (Tegretol)FDA LinkGeneric 01/2019
1	Phenytoin (Dilantin)FDA LinkGeneric 01/2019
1	Mexiletine (Mexitil)FDA LinkGeneric 01/2019
1	Pregabalin (Lyrica)FDA Link 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	ametantrone (HAQ)IBA 01/2018
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2018
1	Adrenal Cortex Hormones (Corticosteroids)IBA 03/2016
1	Cerebroside-Sulfatase (Arylsulfatase A)IBA 01/2016
1	AlarminsIBA 09/2015
1	HMGB1 Protein (HMG1)IBA 09/2015
1	1,3-dipropyl-8-phenylxanthineIBA 06/2015
1	Azathioprine (Imuran)FDA LinkGeneric 06/2015
1	Thomsen-Friedenreich antigenIBA 05/2013
1	Cancer VaccinesIBA 05/2013
1	Immunoglobulin M (IgM)IBA 05/2013
1	Uridine Diphosphate (UDP)IBA 03/2013
1	N-acylmannosamine kinaseIBA 03/2013
1	Racemases and Epimerases (Epimerases and Racemases)IBA 03/2013
1	Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA 03/2013
1	AcetylglucosamineIBA 03/2013
1	Crystallins (Crystallin)IBA 03/2013
1	Prednisone (Sone)FDA LinkGeneric 12/2012
1	Intravenous Immunoglobulins (IVIG)FDA Link 12/2012
1	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 05/2012
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2012
1	thioflavin TIBA 04/2012
1	Indicators and Reagents (Reagents)IBA 04/2012
1	Tyrosine (L-Tyrosine)FDA Link 04/2012
1	3-nitrotyrosineIBA 04/2012
1	Histocompatibility Antigens Class IIIBA 02/2011
1	Alemtuzumab (Campath)FDA Link 06/2009

Therapy/Procedure

10	Therapeutics 01/2022 - 08/2003
3	Immunotherapy 01/2017 - 12/2012
1	Intraperitoneal Injections 01/2020